KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
6.36
Human Site:
S904
Identified Species:
10.77
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
S904
R
K
E
P
S
E
I
S
E
A
S
E
E
K
R
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S904
R
K
E
P
S
E
I
S
E
A
S
E
E
K
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
L607
Y
S
R
E
A
Y
H
L
P
L
P
V
A
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
A964
R
K
E
P
P
D
T
A
S
S
G
D
Q
K
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
G564
T
V
A
L
G
Q
L
G
D
D
R
E
M
V
Q
Chicken
Gallus gallus
Q5F3P8
2008
223067
A957
R
K
E
P
P
E
A
A
S
A
G
D
Q
K
R
Frog
Xenopus laevis
Q66J90
1938
216239
A922
R
K
E
P
P
D
A
A
L
A
G
D
Q
K
R
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
E960
L
D
S
E
G
E
E
E
E
E
T
S
G
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
S872
E
D
S
N
V
E
I
S
D
T
A
R
S
K
I
Honey Bee
Apis mellifera
XP_395451
1406
159180
L683
K
I
K
A
P
S
P
L
P
Q
D
E
D
S
R
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
I784
A
E
D
I
R
Q
Q
I
M
R
Q
C
F
A
A
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
A1111
D
F
K
P
E
Q
L
A
N
L
N
F
P
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
K357
F
V
E
I
N
V
K
K
L
Q
K
L
Q
E
N
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
R590
D
D
Q
D
R
R
R
R
D
E
E
A
D
I
E
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
0
N.A.
40
N.A.
N.A.
6.6
53.3
46.6
20
N.A.
26.6
13.3
0
6.6
P-Site Similarity:
100
100
N.A.
6.6
N.A.
73.3
N.A.
N.A.
33.3
73.3
73.3
26.6
N.A.
40
33.3
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
0
15
29
0
29
8
8
8
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
15
22
8
8
0
15
0
0
22
8
8
22
15
0
0
% D
% Glu:
8
8
43
15
8
36
8
8
22
15
8
29
15
8
22
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% F
% Gly:
0
0
0
0
15
0
0
8
0
0
22
0
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
15
0
0
22
8
0
0
0
0
0
8
8
% I
% Lys:
8
36
15
0
0
0
8
8
0
0
8
0
0
50
0
% K
% Leu:
8
0
0
8
0
0
15
15
15
15
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
8
0
8
0
0
0
8
% N
% Pro:
0
0
0
43
29
0
8
0
15
0
8
0
8
0
0
% P
% Gln:
0
0
8
0
0
22
8
0
0
15
8
0
29
0
15
% Q
% Arg:
36
0
8
0
15
8
8
8
0
8
8
8
0
0
43
% R
% Ser:
0
8
15
0
15
8
0
22
15
8
15
8
8
8
0
% S
% Thr:
8
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% T
% Val:
0
15
0
0
8
8
0
0
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _